RMD Review: July 2024

Diarrhea

The woman wake up for go to restroom. People with diarrhea problem concept

The goal of this review is to briefly review the history, physical, workup, and treatment specific to acute diarrhea in the urgent care clinical setting. Acute diarrhea is limited to less than 14 days. Below is not the complete chart of a patient with diarrhea but simply specific items that must be done for diarrhea.

Epidemiology

Diarrhea for 1-3 days should be considered viral as 73% are viral.

Diarrhea for 3-6 days should be considered bacterial as the percentage shifts from viral to bacterial.

Diarrhea for over 6 days is more likely to be parasitic and must send stool studies, as noted below.

History

How many days has diarrhea been present, and is the severity improving, worsening, or the same?

How many stools per day, volume of stool, and if there is a particular smell?

What is the color and consistency of stool (blood, mucus, watery, semi-solid, etc.)?

Has the patient had exposure to others with a similar illness?

Has the patient recently taken antibiotics or are they a healthcare worker?

Review of Systems (ROS)

Fever with Tmax if present, light-headedness, abdominal pain.

Past, Family, and/or Social History (PFSH)

Cardiac disease, immunocompromise, inflammatory bowel disease, and pregnancy.

Physical

Volume status (vitals, mucus membranes, skin turgor). Complete abdominal pain.

Labs

Urinalysis can aid volume status. Chemistry panel if the volume is very depleted. 

Stool studies are indicated if more than 1 week, more than 6 stools a day, severe abdominal pain, hypovolemia, bloody diarrhea, high fever, and comorbid conditions listed above.

Treatment

  • Supportive care and good hydration are the mainstay treatments for almost all diarrhea.
  • Symptomatic medication.
  • Loperamide can be used cautiously when there is no fever and stools are not bloody. The dose is 4mg initially, 2mg after each unformed stool for less than 2 days, and a maximum daily dose of 16mg. 
  • Empiric antibiotics.
  • Azithromycin 1g once or 500mg QDay for 3 days.
  • Ciprofloxacin 750mg once or 500mg BID 3 days
  • Indications for empiric antibiotics   
  • Fever >101.3, significant hypovolemia, >6 stools/day without any noticeable improvement, severe abdominal pain, >70 years old, comorbidities listed above 
  • Specific and targeted treatments may vary based on the results of stool studies 

Sources

Author

Daniel Ralston, MD
Regional Medical Director
Peachtree Immediate Care